611 W. Union Street
Benson, AZ 85602
(520) 586-0800

member support line
M-F 5pm-8pm
24/7 weekends/holidays

AzCH Nurse Assist Line


611 W. Union Street
Benson, AZ 85602
(520) 586-0800

AzCH Nurse Assist Line


powered by centersite dot net
Health Sciences
Basic InformationLatest News
AHA News: Want a Personalized Diet to Prevent Disease? Nutrition Scientists Are Working on ItScience Brings Shortcut to Spotting 50 Rare Genetic DiseasesAmazon Tribes May Have Lowest Rate of Dementia in the WorldBrain Changes May Fuel 'Long COVID' Anxiety, ConfusionHow COVID-19 Can Change the BrainEven a Little Drinking Ages the Brain: StudyCould Your Blood Type Make COVID Worse?Blood Test Marker Could Gauge Risks After Heart SurgeryGene Tests Often Reveal Unknown RelativesResearchers Map Out Enormous Human Family TreeFour-Legged Friends Could Be Friend to Your BrainScience Pinpoints the Brain's 'Singing Center'Soccer Headers May Disrupt Key 'Pathways' in the BrainScientists Create 'Universal' Donor Organs Where Blood Type Doesn't MatterAre 'Good' Germs in Your Gut Key to a Healthy Brain?Acne's Genetic Secrets Could Bring Better TreatmentsNew Technology Restores Movement After Spinal Cord ParalysisBrain Changes Appear by Middle Age After Years of High Blood PressureBrain's Decline Accelerates in Years After Heart AttackTen Years After Gene Therapy for Leukemia, Doctors Say Patients CuredDid Your Gene Screen Turn Up Dangerous DNA? Study Finds Real Risk Is LowAHA News: Statistics Report Offers Snapshot of the Nation's Brain Health – And a Guide to Protecting ItAHA News: Obesity Harms Brain Health Throughout Life – Yet Scientists Don't Know WhyEven a Little Exercise May Help Slow Parkinson'sScientists ID Genes That Make Your ​FingerprintsCould the 'Alzheimer's Gene' Raise Risks for Severe COVID-19?Genes 'Switched On' Much Earlier in Human Embryos Than ThoughtFormaldehyde in the Workplace Tied to Later Brain IssuesAHA News: Making a Lifetime of Good Brain Health a Global PriorityNFL Players Face 4 Times the Odds of ALSCould Gene Therapy Help Cure Sickle Cell Disease?Toxins in Wildfire Smoke May Make Their Way Into BrainMRI Might Spot Concussion-Linked CTE in Living PatientsCertain Blood Thinners Can Raise Risk of 'Delayed' Bleeding After Head InjuryAHA News: Former NFL Players With Lots of Concussions May Have Higher Stroke RiskMore Years Playing Football, More Brain Lesions on MRI: StudyNew Insights Into What Might Drive Parkinson's DiseaseBrain's 'White Matter' Changes in People With AutismWearable Vibration Device May Ease Parkinson's TremorNeurologists' Group Issues New Treatment Guidelines for Early Parkinson'sGene Therapy Could Be Big Advance Against HemophiliaBlood Test Looks at Patients' Whole Genome to Spot Rare Inherited DiseasesSales of Unproven, Unapproved Stem Cell Therapies Are BoomingHow Bilingual Brains Shift Quickly Between LanguagesMouse Study Offers Hope for Gene Therapy Against Parkinson's DiseaseInsomnia Tied to Raised Risk of AneurysmAHA News: Could the Path to Better Brain Health Involve Better Mouth Care?More Americans Are Dying From Parkinson's Disease: StudyTen Years On, Gene Therapy Still Beating Most Cases of 'Bubble Boy' Immune DiseaseResearchers Find Better Way to Fight Breast Cancer That Has Spread to Brain
Questions and AnswersLinksBook Reviews
Related Topics

Medical Disorders
Mental Disorders
Mental Health Professions

New Technology Restores Movement After Spinal Cord Paralysis

HealthDay News
Updated: Feb 7th 2022

new article illustration

MONDAY, Feb. 7, 2022 (HealthDay News) -- A motorcycle crash left Michel Roccati with complete lower-body paralysis from a devastating spinal cord injury.

That was in 2017.

But now, the Italian native is walking again, courtesy of groundbreaking Swiss research that restores motor function within one day by means of carefully targeted electrical stimulation.

"At the beginning, I was unable to move the muscles of the legs, and I feel nothing," Roccati recalled recently.

Now he can stand, walk and do stairs. In fact, "everything I have in mind to train I can do with the stimulation," Roccati said at a press briefing hosted by Nature Medicine, which recently published the findings.

According to the World Health Organization, every year from 250,000 to a half-million people around the world suffer a seriously disabling spinal cord injury, most often the result of a fall, violence or, like Roccati, a traffic accident. Compared to people without this injury, they are two to five times more likely to die prematurely.

Roccati is one of three patients enrolled in the Swiss effort, all men between 29 and 41 years old. Each had experienced a complete spinal cord injury at least a year prior to the study's launch.

"This means that they could not move the legs, and they did not have any sensation over the legs," said study co-author Dr. Jocelyne Bloch, a neurosurgeon and chief of the functional neurosurgery unit at Lausanne University Hospital in Switzerland.

Speaking at the briefing, Bloch noted that in 2020 the three men underwent surgery at NeuroRestore in Lausanne to implant a pacemaker in the abdomen and electrodes directly onto the spinal cord.

Those electrodes are themselves an important innovation, explained study colleague and neuroscientist Grégoire Courtine.

Constructed to be permanent, they are "precisely positioned to target all the regions of the spinal cord that are relevant to activate trunk and leg muscles," said Courtine, who is with the Swiss Federal Institute of Technology in Lausanne.

The electrodes were then paired with new software that facilitated a highly personalized mapping of each patient's spinal cord, Courtine said in the briefing.

The software also provides a simple tablet-based interface that allows patients and physical therapists to easily set up semi-automated stimulation programs that enable a variety of movements.

Patients can operate these programs themselves, via a tablet and small remote controls that can communicate wirelessly to the patient's pacemaker.

For Roccati, all this meant that following a 10-day post-surgery recovery period, rehab began -- and "I was able to walk after one day," he said. The remote controls are attached to his walker.

"Thanks to this technology, all three patients, immediately after surgery, were able to stand up and walk," said Bloch during the briefing. Pedaling, swimming, and torso movement were also enabled. None reported any pain or side effects triggered by the stimulation.

Still, Bloch noted that motor control "was not perfect at the very beginning." And Courtine emphasized that regaining movement post-surgery is a process, "not a miracle," with patients initially needing a lot of physical support. Also, "the recovery of sensation is very different from one patient to the other," he added.

"But what it does is enable an immediate ability to train," Courtine noted. And because the technology is small and portable, that training can take place out in the real world.

Every day, with the stimulation turned on, "Michel is able to stand for two hours, and he walks almost 1 kilometer (.6 of a mile) straight, without stopping," in addition to climbing up and down stairs, said Courtine. "When the stimulation is turned off, he had some recovery, but to a very limited extent."

Bloch said the technology would almost certainly work equally well among female paralysis patients.

And while future research may expand what's possible, Bloch acknowledged one key limitation: "We need at least 6 centimeters of healthy spinal cord under the lesion. That's where we implant our electrodes."

Claudia Angeli, director of the University of Louisville's Spinal Cord Injury Research Center in Kentucky, agreed the Swiss team's work is "encouraging," but said other approaches also show merit.

"This group is using a very specific stimulation" signaling method, while alternative efforts attempt to enable motor control via direct stimulation of brain signals, she said.

Such alternative approaches "have shown similar results," Angeli noted. "There has not been a direct comparison of the two methods, but both are showing promise for recovery following spinal cord injury."

Meanwhile, the Swiss team has a trial in the works in the United States. The researchers noted that the U.S. Food and Drug Administration has approved a "breakthrough devices" designation to expedite the process whereby the technology could become commercially available. This designation would also ensure coverage through the Medicare Coverage of Innovative Technology program if larger clinical trials are successful, the researchers said.

As for Roccati, after nine months of Lausanne-based rehab, he now lives independently in Italy. "I continued rehab at home, working alone, with all the devices," he said. "And I see improvements every day."

More information

There's more on spinal cord injuries and paralysis at Christopher & Dana Reeve Foundation.

SOURCES: Claudia Angeli, PhD, assistant professor, School of Engineering, University of Louisville, and director, Kentucky Spinal Cord Injury Research Center; press briefing, Feb. 2, 2022, and Nature Medicine, Feb. 2, 2022