611 W. Union Street
Benson, AZ 85602
(520) 586-0800

LaFrontera
member support line
1-520-279-5737
M-F 5pm-8pm
24/7 weekends/holidays

AzCH Nurse Assist Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530



SEABHS
611 W. Union Street
Benson, AZ 85602
(520) 586-0800

AzCH Nurse Assist Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530


powered by centersite dot net
Medical Disorders
Resources
Basic InformationLookupsLatest News
New Hormonal Pill May Boost Outcomes for Older Breast Cancer PatientsHad COVID? Getting Vaccinated Strengthens Your Antibodies to New VariantsU.S. to Pump $400 Million Into Vaccination Programs for Other CountriesPandemic Sent Americans' Blood Pressure Numbers SkywardWere Cancer Patients Neglected in U.S. COVID Vaccine Rollout?Young People Recover Quickly From Rare Heart Side Effect of COVID VaccineMore Evidence That Pandemic Delayed Cancer DiagnosesHigh Heart Rate Linked to Dementia RiskCOVID Vaccine, Testing Demand Overwhelming PharmaciesOmicron Spreading Through Africa Twice as Fast as Delta DidWith Holidays Ahead, COVID Boosters a Must for People With Weak Immune SystemsKeep Your Holidays Allergy-Free This YearDo Immune-Based Cancer Drugs Work Better in Men?Gene Found in Amish Helps Protect Their HeartsOmicron May Overcome Prior COVID InfectionWindy Days Are Safer Days When It Comes to COVID-19Most Vaccinated Adults Plan to Get Boosters: PollStudy Finds Delta Somewhat Resistant to Vaccines — What About Omicron?Is the Mumps Vaccine Becoming Less Effective?Vaping Can Trigger Gene Changes in Cells: StudyPfizer or Moderna? Head-to-Head Study Shows One Shot Has an EdgeSurvivors of Severe COVID Face Doubled Risk for Death a Year LaterKids With Uncontrolled Asthma at Higher Odds for Severe COVID-19Nearly 7% of U.S. Kids Have Had a Head Injury or ConcussionFirst U.S. Omicron Case Reported in California'Ultra-Processed' Foods Up Odds for a Second Heart Attack or StrokeCDC to Toughen COVID Testing for International TravelersAHA News: Irregular Heartbeat Risk Linked to Frequent Alcohol Use in People Under 40Certain Blood Thinners Can Raise Risk of 'Delayed' Bleeding After Head InjuryFDA Panel Gives Support to Merck's COVID Antiviral PillLong-Haul COVID Can Include Chronic Fatigue: StudyVaccines, Boosters Should Protect Against Severe COVID, Even With Omicron: FauciPfizer to Seek FDA Approval of Boosters for Teens Ages 16-17Regeneron Says Its Antibody Cocktail Likely Weakened by Omicron VariantCOVID May Trigger Heart Condition in Young AthletesMany People With High Blood Pressure May Take a Drug That Worsens It: StudyBiden Pushes Vaccines, Masks as Best Defense Against Omicron VariantHow Easily Can Singing Spread COVID-19?New Insights Into What Might Drive Parkinson's DiseaseHot Days Can Send Even Younger Folks to the ERRed Light in Morning May Protect Fading Eyesight: StudyMerck's COVID Pill Appears Effective, But May Pose Pregnancy Risks: FDAVaccine Makers Already Testing Their Shots Against Omicron VariantWhat Experts Know About the Omicron 'Variant of Concern'Gout Drug Colchicine Won't Help Fight COVID-19What You Need to Know About Stomach CancerFetal Infection With COVID-19 Possible, But UnlikelyCOVID Protection Wanes After 2 Doses of Pfizer Vaccine: StudyRural Hospitals' ERs Just as Effective as Urban Ones: Study1 in 5 Avoided Health Care During Pandemic, Study Finds
Questions and AnswersLinksBook Reviews
Related Topics

Cancer
Men's Health
Women's Health

Animal Study Offers Hope for a Vaccine Against Lyme Disease

HealthDay News
by Robert Preidt
Updated: Nov 23rd 2021

new article illustration

TUESDAY, Nov. 23, 2021 (HealthDay News) -- An experimental Lyme disease vaccine shows promise in animal studies and could also help protect against other tick-borne diseases, researchers say.

The vaccine — which relies on the same mRNA technology used by some COVID-19 vaccines — protected guinea pigs against infection by Borrelia burgdorferi, the bacterium that causes Lyme disease.

The vaccine doesn't trigger the immune system to attack B. burgdorferi. Instead, it prompts a quick response in the skin to certain proteins in tick saliva, which reduces the amount of time a tick has to infect the host, the Yale University team explained.

"The vaccine enhances the ability to recognize a tick bite, partially turning a tick bite into a mosquito bite," said senior author Dr. Erol Fikrig, a professor of medicine and epidemiology at Yale, in New Haven, Conn.

"When you feel a mosquito bite, you swat it," he explained. "With the vaccine, there is redness and likely an itch so you can recognize that you have been bitten and can pull the tick off quickly, before it has the ability to transmit B. burgdorferi."

Compared to unvaccinated guinea pigs, those that were vaccinated quickly developed redness at a tick bite site. As long as ticks were removed when redness appeared, none of the vaccinated guinea pigs were infected. About half of the unvaccinated guinea pigs became infected after ticks were removed, the findings showed.

When a single infected tick was attached to vaccinated guinea pigs and not removed, none was infected, compared with 60% of unvaccinated guinea pigs. But if three ticks remained attached to vaccinated guinea pigs, their protection wasn't as strong, according to the report published Nov. 17 in the journal Science Translational Medicine.

The researchers also found that ticks attached to vaccinated guinea pigs were unable to feed aggressively and dislodged more quickly than those on unvaccinated guinea pigs.

At least 40,000 cases of Lyme disease are reported each year in the United States, but the actual numbers of infections could be 10 times greater, the researchers noted. Other tick-borne diseases have also spread in many areas of the United States, they added.

"There are multiple tick-borne diseases, and this approach potentially offers more broad-based protection than a vaccine that targets a specific pathogen," Fikrig said in a university news release.

"It could also be used in conjunction with more traditional, pathogen-based vaccines to increase their efficacy," he added.

More research is needed to discover ways that proteins in saliva can prevent infection, Fikrig said, and human clinical trials would be needed to assess the vaccine's effectiveness in people.

More information

The American Academy of Family Physicians has more on Lyme disease.

SOURCE: Yale University, news release, Nov. 17, 2021