611 W. Union Street
Benson, AZ 85602
(520) 586-0800

LaFrontera
member support line
1-520-279-5737
M-F 5pm-8pm
24/7 weekends/holidays

AzCH Nurse Assist Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530



SEABHS
611 W. Union Street
Benson, AZ 85602
(520) 586-0800

AzCH Nurse Assist Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530


powered by centersite dot net
Medical Disorders
Resources
Basic InformationLookupsLatest News
New Hormonal Pill May Boost Outcomes for Older Breast Cancer PatientsHad COVID? Getting Vaccinated Strengthens Your Antibodies to New VariantsU.S. to Pump $400 Million Into Vaccination Programs for Other CountriesPandemic Sent Americans' Blood Pressure Numbers SkywardWere Cancer Patients Neglected in U.S. COVID Vaccine Rollout?Young People Recover Quickly From Rare Heart Side Effect of COVID VaccineMore Evidence That Pandemic Delayed Cancer DiagnosesHigh Heart Rate Linked to Dementia RiskCOVID Vaccine, Testing Demand Overwhelming PharmaciesOmicron Spreading Through Africa Twice as Fast as Delta DidWith Holidays Ahead, COVID Boosters a Must for People With Weak Immune SystemsKeep Your Holidays Allergy-Free This YearDo Immune-Based Cancer Drugs Work Better in Men?Gene Found in Amish Helps Protect Their HeartsOmicron May Overcome Prior COVID InfectionWindy Days Are Safer Days When It Comes to COVID-19Most Vaccinated Adults Plan to Get Boosters: PollStudy Finds Delta Somewhat Resistant to Vaccines — What About Omicron?Is the Mumps Vaccine Becoming Less Effective?Vaping Can Trigger Gene Changes in Cells: StudyPfizer or Moderna? Head-to-Head Study Shows One Shot Has an EdgeSurvivors of Severe COVID Face Doubled Risk for Death a Year LaterKids With Uncontrolled Asthma at Higher Odds for Severe COVID-19Nearly 7% of U.S. Kids Have Had a Head Injury or ConcussionFirst U.S. Omicron Case Reported in California'Ultra-Processed' Foods Up Odds for a Second Heart Attack or StrokeCDC to Toughen COVID Testing for International TravelersAHA News: Irregular Heartbeat Risk Linked to Frequent Alcohol Use in People Under 40Certain Blood Thinners Can Raise Risk of 'Delayed' Bleeding After Head InjuryFDA Panel Gives Support to Merck's COVID Antiviral PillLong-Haul COVID Can Include Chronic Fatigue: StudyVaccines, Boosters Should Protect Against Severe COVID, Even With Omicron: FauciPfizer to Seek FDA Approval of Boosters for Teens Ages 16-17Regeneron Says Its Antibody Cocktail Likely Weakened by Omicron VariantCOVID May Trigger Heart Condition in Young AthletesMany People With High Blood Pressure May Take a Drug That Worsens It: StudyBiden Pushes Vaccines, Masks as Best Defense Against Omicron VariantHow Easily Can Singing Spread COVID-19?New Insights Into What Might Drive Parkinson's DiseaseHot Days Can Send Even Younger Folks to the ERRed Light in Morning May Protect Fading Eyesight: StudyMerck's COVID Pill Appears Effective, But May Pose Pregnancy Risks: FDAVaccine Makers Already Testing Their Shots Against Omicron VariantWhat Experts Know About the Omicron 'Variant of Concern'Gout Drug Colchicine Won't Help Fight COVID-19What You Need to Know About Stomach CancerFetal Infection With COVID-19 Possible, But UnlikelyCOVID Protection Wanes After 2 Doses of Pfizer Vaccine: StudyRural Hospitals' ERs Just as Effective as Urban Ones: Study1 in 5 Avoided Health Care During Pandemic, Study Finds
Questions and AnswersLinksBook Reviews
Related Topics

Cancer
Men's Health
Women's Health

Booster Shots Prompt Stronger, Longer Protection Than Original Shots: Study

HealthDay News
by Robert Preidt
Updated: Nov 22nd 2021

new article illustration

MONDAY, Nov. 22, 2021 (HealthDay News) -- COVID-19 booster shots trigger much stronger and longer protection than full vaccination with two doses of the Pfizer or Moderna vaccines, according to a small study.

It also found that the response to a booster is even greater in fully vaccinated people who have had infections.

"Because these antibody levels are so robust, the booster could potentially give us protection for a longer duration than what we saw for two doses of the vaccine," study co-author Alexis Demonbreun said in a Northwestern University news release. She is an assistant professor of pharmacology at Northwestern's Feinberg School of Medicine in Chicago.

For this study, the researchers analyzed blood samples from 33 healthy, fully vaccinated young adults in the Chicago area. Their median age was 43, meaning half were older, half younger.

Nine months after they had two doses of the Pfizer or Moderna vaccines, their neutralizing antibody levels to SARS-CoV-2 had decreased about 10-fold, the study found. After a booster shot, antibody levels rose 25-fold -- five times higher than after two doses of the vaccine.

Booster antibodies were 50 times higher than those from natural infection, according to findings published Nov. 21 on medRxiv, a preprint server for health sciences.

Because the study has not yet been peer-reviewed, it should be considered a preliminary finding.

The researchers said booster doses trigger a high level of neutralizing antibodies against the Delta variant, which should provide much protection. However, the response was even higher against the original version of the virus because it's the one that vaccines target.

Co-author Thomas McDade said the findings are relevant to anyone who is considering a booster shot.

"We know the mRNA vaccines provide a high level of protection against serious cases of COVID-19 that lead to hospitalization or death," said McDade, a fellow with the university's Institute for Policy Research.

"But immunity wanes over time -- particularly levels of antibodies that help prevent infection -- and we are seeing higher rates of breakthrough infections as a result, particularly in combination with the rise of the more infectious Delta variant," he said in the release.

Demonbreun said researchers think the robust effect of booster shots observed in this small group will be mirrored in much larger population.

Since the pandemic began, the researchers have been evaluating antibody responses from natural infection and after each dose of COVID vaccines, and have published a number of studies with their findings.

They will continue to evaluate antibody levels over time and monitor breakthrough infections to assess waning immunity.

More information

The U.S. Centers for Disease Control and Prevention has more on COVID-19 vaccine booster shots.

SOURCE: Northwestern University, news release, Nov. 22, 2021