611 W. Union Street
Benson, AZ 85602
(520) 586-0800

member support line
M-F 5pm-8pm
24/7 weekends/holidays

AzCH Nurse Assist Line


611 W. Union Street
Benson, AZ 85602
(520) 586-0800

AzCH Nurse Assist Line


powered by centersite dot net
Medical Disorders
Basic InformationLookupsLatest News
Is Rise in Liver Damage Tied to More Drinking During Lockdowns?Bike-Linked Head Injuries Plummet for U.S. Kids, But Not AdultsDialysis Patients Have Weaker Response to COVID Vaccine: StudyWith New Mask Guidance Comes the Challenge of Following ItWeight-Loss Surgery Might Also Help Prevent CataractsAHA News: What to Tell Your Young Teen About Their Shot at the COVID-19 VaccineWhat Works Best to Ease Recurrent Ear Infections in Kids?Mixing COVID Vaccines Might Raise Odds for Minor Reactions: StudyCOVID More Lethal for People Living With HIVNew Drug Shows Promise Against Tough-to-Manage AsthmaFully Vaccinated Can Shed Masks in Most Outdoor, Indoor Settings: CDCAHA News: 5 Things to Know About Blood Pressure Before It's a ProblemModerna Vaccine Can Trigger Red, Itchy 'COVID Arm,' But It's TemporaryCould a Vaccine Against Future Pandemics Be on the Way?Debunking Social Media Myth, Study Finds COVID Vaccine Won't Harm PlacentaU.S. Seniors Are Getting Fewer Abdominal SurgeriesMost Severe COVID Cases Involve Neuro Issues, and They're More Often FatalAny COVID-19 Infection Raises Odds for Lingering Symptoms, Study FindsNew Insights Into Treating Mild Head InjuriesAlcohol Is No Friend to Social DistancingGene-Targeted Drug Shows Promise Against a Form of Pancreatic CancerFDA Approves Emergency Use of Pfizer Vaccine for Those Aged 12 to 15Ibuprofen, Similar Painkillers Won't Raise Risks for COVID PatientsObesity Raises Odds for Many Common CancersAsthma Attacks Plummeted During PandemicWhy Sleep Raises Risk for Sudden Death in People With EpilepsyLockdown Loneliness Making Things Even Tougher for Cancer PatientsCOVID Vaccines May Still Leave Organ Transplant Recipients UnprotectedPfizer, Moderna or J&J? An Expert Answers Your QuestionsHow Summer Camps Can Shield Your Kids from Allergies, Asthma & COVIDCould Your Child Have a Heart Defect? Know the Warning SignsGene Tied to Balding May Also Raise COVID Risks for MenTime Spent in ICU Linked to Higher Odds for Suicide LaterState of Mind Matters for Survival After Heart AttackFailing Kidneys Could Bring Higher Dementia RiskAir Pollution Can Harm Kids' Hearts for a LifetimePoll Finds Many Parents Hesitant to Get Younger Kids VaccinatedObesity More Deadly for Men Than Women When COVID StrikesIsrael Study: Pfizer Vaccine Gives 95% Protection Against Illness, Hospitalization & DeathReal-World Studies Show Pfizer Vaccine Shields Against COVID Variants1 in 4 U.S. Teens Has Had a Concussion: StudyWhat's the Right Amount of Sleep for a Healthy Heart?U.S. COVID Outlook Shows Big Improvement by July'Prediabetes' Raises Odds for Heart Attack, StrokeA Vitamin Could Be Key to Women's Pain After Knee ReplacementBiden Sets New Goal of Vaccinating 70% of Americans by July 4Wildfires Are Changing the Seasonal Air Quality of the U.S. WestMany Americans Wrong About Sun's Skin Cancer Dangers: PollNot Just About Antibodies: Why mRNA COVID Vaccines May Shield From VariantsYou Got Your COVID Shot: What to Do With That Vaccine Card
Questions and AnswersLinksBook Reviews
Related Topics

Men's Health
Women's Health

Hormone Treatments May Raise Blood Pressure in Transgender People

HealthDay News
by Cara Murez
Updated: Apr 19th 2021

new article illustration

MONDAY, April 19, 2021 (HealthDay News) -- Monitoring blood pressure is important for transgender people, according to new research, which found changes in systolic blood pressure after the start of gender-affirming hormone therapy.

Transgender men and transgender women have a higher burden of heart attack, stroke and related conditions, the study noted.

Gender-affirming hormone therapy isn't new. Doctors have prescribed the hormones for more than 25 years, but little is known about their impact on high blood pressure rates and how the effects change over time.

"There are many important gaps in our knowledge about the effects of hormone therapy for transgender people," said senior author Dr. Michael Irwig, director of transgender medicine at Beth Israel Deaconess Medical Center in Boston. The research was published April 19 in the journal Hypertension.

"This study examined the time course and magnitude of the effects of gender-affirming hormones on blood pressure," Irwig said in a journal news release.

He and his colleagues followed 470 patients who began gender-affirming hormone therapy from early 2007 to mid-2015. They described their work as the largest and longest observational study of its kind.

Participants were all at least 17 years old, with 247 who were transfeminine (assigned male at birth but identify as female) and 223 who were transmasculine (assigned female at birth but identify as male). About 27% self-identified as non-white, and 16% identified as Hispanic.

Researchers measured participants' blood pressure before hormone therapy began and for up to 57 months -- nearly five years.

Within two to four months of beginning hormone therapy, transgender women saw an average drop of 4.0 mm Hg in their systolic blood pressure. Transgender men saw an average increase of 2.6 mm Hg.

Systolic blood pressure, the top number in a blood pressure reading, measures the force your heart exerts on artery walls each time it beats.

The prevalence of stage 2 high blood pressure fell from 19% to 10% in the transfeminine group within two to four months of starting hormone therapy, the study found.

The use of testosterone in transgender men could lead to an increased risk for heart attack or stroke if they also have untreated high blood pressure, researchers said.

Some participants saw blood pressure rates trend in the opposite direction compared to the majority of people with the same gender identity. Researchers said that would require more study to understand.

Previous research has found that transgender men were almost five times as likely to report having a heart attack compared to cisgender women (those assigned female at birth and identify as female).

Transgender women, meanwhile were more than 2.5 times more likely to have reported a heart attack than cisgender women. They did not have a significant increase in heart attack incidence when compared with cisgender men.

A systematic review conducted in 2020 found most of the studies examining gender-affirming hormones and blood pressure had too few participants to detect statistically significant differences in blood pressure.

Researchers noted that the new study also had some limitations. Among them: Most patients were on the same formulation of intramuscular testosterone or oral estrogen, so the effects of other formulations need further study in a more diverse group.

A 2020 Scientific Statement from the American Heart Association said it is paramount to include LGBTQ health in clinical training and license requirements for health care professionals in order to better address heart health disparities.

More information

Johns Hopkins Medicine has more information on transgender health.

SOURCE: Hypertension, news release, April 19, 2021