611 W. Union Street
Benson, AZ 85602
(520) 586-0800

Health Choice Integrated Care crisis Line
1-877-756-4090

AzCH Nurse Assist Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530



SEABHS
611 W. Union Street
Benson, AZ 85602
(520) 586-0800

AzCH Nurse Assist Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530


powered by centersite dot net

Getting Started
Here are some forms to get started. These can be printed and brought with you so that you can pre-fill out some known info ahead of time. More...


Health Sciences
Resources
Basic InformationLatest News
In a First, Doctors Use Robotics to Treat Brain AneurysmSkiers Study Suggests Fitness May Stave Off Parkinson'sCRISPR Gene Editing Creates 'Designer' Immune Cells That Fight CancerGene Variant Ups Dementia Risk in Parkinson's Patients: StudyGene Variation May Protect Against Alzheimer's: StudyYoung-Onset Parkinson's May Start in the Womb, New Research SuggestsNew Gene Study Unravels Cancer's SecretsDoes Size Matter? Volume of Brain Area Not Always Tied to Memory, ThinkingGene Test Might Spot Soccer Players at High Risk for Brain TroubleSevere Deprivation in Childhood Has Lasting Impact on Brain SizeIn the Future, Could Exercise's Benefits Come in a Pill?Could Brain Scans Spot Children's Mood, Attention Problems Early?Brain Damage Changes Over Time in Boxers, MMA FightersSpecial 'Invisible' Dye Could Serve as Skin's Vaccination RecordCancer Drug Shows Promise for Parkinson's Patients'Smart' Contact Lenses Might Also Monitor Eye HealthCould Obesity Alter a Child's Brain Structure?Playing Sports Might Sharpen Your HearingAntarctic Study Shows Isolation, Monotony May Change the Human BrainCould MS Have Links to the Herpes Virus?Ultrasound Treatment Might Ease Parkinson's TremorsAnimal Study Offers Hope for Treating Traumatic Brain InjuriesA Gene Kept One Woman From Developing Alzheimer's -- Could It Help Others?Could AI Beat Radiologists at Spotting Bleeds in the Brain?Pro Soccer Players More Likely to Develop Dementia: StudyExtinct Human Species Passed on Powerful Immune System GeneScientists ID Genes Tied to Left-HandednessScientists Creating Gene Map of Human 'Microbiome'New DNA Blood Test May Help Guide Breast Cancer TreatmentFootball Head Trauma Linked Again to Long-Term Brain DamageMore 'Buyer Beware' Warnings for Unregulated Stem Cell Clinics3-D Printers Might Someday Make Replacement HeartsOne Gene Change 2 Million Years Ago Left Humans Vulnerable to Heart AttackHow to Protect Your DNA for Big Health BenefitsBones Help Black People Keep Facial Aging at BayGene Test Might Someday Gauge Your Heart Attack RiskYour Gut Bacteria Could Affect Your Response to MedsIt's Never Too Late for New Brain CellsSensor-Laden Glove Helps Robotic Hands 'Feel' ObjectsAn Antibiotic Alternative? Using a Virus to Fight BacteriaBrain Sharpens the Hearing of the Blind, Study FindsMind-Reading Tech Could Bring 'Synthetic Speech' to Brain-Damaged PatientsCan Obesity Shrink Your Brain?Will You Get Fat? Genetic Test May TellMagnet 'Zap' to the Brain Might Jumpstart Aging MemoryWhy More Patients Are Surviving an AneurysmIsraeli Team Announces First 3D-Printed Heart Using Human CellsPoverty Could Leave Its Mark on GenesNFL Retirees Help Scientists Develop Early Test for Brain Condition CTEBrain 'Zap' Might Rejuvenate Aging Memory
Questions and AnswersLinksBook Reviews
Related Topics

Medical Disorders
Mental Disorders
Mental Health Professions

Gene Test Might Someday Gauge Your Heart Attack Risk

HealthDay News
by -- Alan Mozes
Updated: Jun 11th 2019

new article illustration

TUESDAY, June 11, 2019 (HealthDay News) -- Can a DNA test predict a person's future heart health? Perhaps, researchers say.

A team of Canadian researchers found that by analyzing a person's entire genome, it might be possible to predict their future heart disease risk.

The so-called "polygenic risk score" analysis looks for key heart disease indicators -- genetic "biomarkers" -- along with an individual's entire genetic blueprint, or genome.

Prior research had already suggested that this type of analysis could determine heart attack risk for people of European descent with no prior heart attack history. But the new analysis suggests the approach can work just as well in other populations.

As lead researcher Guillaume Lettre explained, the polygenic risk score "is like having a snapshot of the whole genetic variation found in one's DNA, and [it] can more powerfully predict one's disease risk. Using the score, we can better understand whether someone is at higher or lower risk to develop a heart problem."

Lettre is an associate professor at the Montreal Heart Institute and the University of Montreal.

One U.S. heart expert agreed that an accurate means of pinpointing heart risk is sorely needed.

Too often "the first symptom of a heart attack is the heart attack [itself]," said Dr. Guy Mintz, who directs cardiovascular health at the Sandra Atlas Bass Heart Hospital in Manhasset, N.Y.

Using tools such as the polygenic risk score, patients at risk could be spotted sooner so that "we can apply more intense improvement in their personal cardiac risk factors at an earlier age," he reasoned.

"I would welcome using this type of precision medicine, individualized medicine, to identify children and adolescents as well as adults" at high risk for heart disease, Mintz said.

In the new analysis, Lettre's group compiled polygenic risk scores for more than 3,600 French Canadian heart disease patients. They then compared those results to those from nearly 7,400 who were heart disease-free.

The result: polygenic risk scores were just as predictively useful for French Canadians as they were for people from other genetic backgrounds, with an ability to accurately pinpoint about 6% to 7% of those tested as having a high risk for heart disease.

One caveat: The analysis was not as useful for those who had already experienced a heart attack. That might be because people with prior attacks tended to be older, and most were already taking drugs, such as statins, to lower their cardiovascular risk, the team theorized.

Dr. Eugenia Gianos directs women's heart health at Lenox Hill Hospital in New York City. Reviewing the findings, she said the new test "held up quite well for its predictive ability for the presence of coronary artery disease."

If the test pans out, it "could innovate how we tailor medical therapies to those at greatest risk earlier in life," she believes.

And Mintz noted that many people live with heart disease for years without knowing it.

"A sobering thought is that heart disease, [arterial] plaque, has been found at autopsy in teenagers and young adults," he said. "So, knowing early on who needs more intense surveillance and therapy could be a game-changer," Mintz explained.

"While the polygenic risk score is less accurate in predicting second heart attacks, I am not worried about that population, because we do a good job in treating this group," he said.

Lettre and his colleagues published their findings June 11 in the journal Circulation: Genomic and Precision Medicine.

More information

There's more on heart attack prevention at the American Heart Association.