611 W. Union Street
Benson, AZ 85602
(520) 586-0800

Health Choice Integrated Care crisis Line
1-877-756-4090

NurseWise 24-Hour Crisis Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530



SEABHS
611 W. Union Street
Benson, AZ 85602
(520) 586-0800

NurseWise 24-Hr Crisis Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530


powered by centersite dot net

Getting Started
Here are some forms to get started. These can be printed and brought with you so that you can pre-fill out some known info ahead of time. More...


Mental Disorders
Resources
Basic InformationLookupsLatest News
Research on Almost 2,000 Brains Brings Insight Into Mental IllnessMore Are Seeking Mental Health Care, But Not Always Those Who Need It MostMental Health Help Becoming Less of a Stigma in MilitaryMajor Injuries Take a Toll on Mental HealthSmoking Persists for Americans With Mental Health IllsSexual Assault Has Long-Term Mental, Physical Impact1 in 3 College Freshmen Faces Mental Health WoesMore Evidence Ties Stress to Heart TroubleIs a Haywire Body Clock Tied to Mood Disorders?From Pigs to Peacocks, What's Up With Those 'Emotional-Support Animals'?Is Evolution of the Human Brain to Blame for Some Mental Disorders?Massive Study Finds Same Genes Drive Many Psychiatric ConditionsDoes Mental Illness Raise Diabetes Risk?'Religious Refusal Laws' May Take Mental Health Toll on LGBT AmericansDisruption of Circadian Rhythm Negatively Impacts Mental HealthNon-Stigmatizing Messages Boost Mental Health Services SupportIncreased Prevalence of Depression, Anxiety After CRCGuidance Offered for Improving Mental Health in WorkplaceCommon Gynecologic Condition Linked to Mental Health IssuesGreat Recession of 2008 Triggered More Than Financial WoesGenetic Variations Impacting Empathy Tied to Psych IssuesEarly Periods Tied to Mental Health Issues Into AdulthoodGender Minorities Have Greater Mental Illness, DisabilityPets Provide Support to People With Mental Health ConditionsPets Good Medicine for Those Battling Mental IllsLimited Evidence for Effect of Cranial Electrical StimulationVirtual Reality-Based CBT Beneficial for Psychotic DisordersAutism, Bipolar and Schizophrenia Share Genetic SimilaritiesSubstantial Unmet Need for Mental Health Care for VeteransMental Health Care Access Differs With Race, InsuranceVA Health System Failing on Mental Health Care: ReportSevere Bullying Tied to Mental Health Woes in TeensMore Sought Mental Health Specialty Care in 2008 to 2015Health Tip: Stay WellU.S. Soldier in Custody Following Slaying of 5 Americans in Iraq
Questions and AnswersLinksBook Reviews
Related Topics

Anxiety Disorders
Bipolar Disorder
Depression: Depression & Related Conditions
Schizophrenia
Eating Disorders

Is Evolution of the Human Brain to Blame for Some Mental Disorders?

HealthDay News
by -- Robert Preidt
Updated: Aug 9th 2018

new article illustration

THURSDAY, Aug. 9, 2018 (HealthDay News) -- Evolutionary changes in the human brain may be responsible for psychiatric illnesses such as schizophrenia and bipolar disorder, new research suggests.

The researchers identified long, noncoding stretches of DNA (called "repeat arrays") in a gene that governs calcium transport in the brain. Their findings were published Aug. 9 in the American Journal of Human Genetics.

"Changes in the structure and sequence of these nucleotide arrays likely contributed to changes in CACNA1C function during human evolution and may modulate neuropsychiatric disease risk in modern human populations," senior author David Kingsley said in a journal news release. Kingsley is a professor of developmental biology at Stanford University in California.

The study authors suggested that the findings could lead to improved treatment for patients with schizophrenia and bipolar disorder, which affect about 3 percent of people worldwide.

Classifying patients based on their repeat arrays may help identify those most likely to respond to current calcium channel drugs, which so far have produced mixed results, Kingsley said.

He added that more research is needed to determine whether patients with a genetic variation of CACNA1C have too much or too little calcium channel activity.

The repeat arrays in the CACNA1C gene occur only in humans. Kingsley said that suggests the arrays may have given humans an evolutionary advantage, even if they increased the risk of conditions such as schizophrenia and bipolar disorder.

More information

The U.S. National Institute of Mental Health has more on schizophrenia.