611 W. Union Street
Benson, AZ 85602
(520) 586-0800

Health Choice Integrated Care crisis Line
1-877-756-4090

NurseWise 24-Hour Crisis Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530



SEABHS
611 W. Union Street
Benson, AZ 85602
(520) 586-0800

NurseWise 24-Hr Crisis Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530


powered by centersite dot net

Getting Started
Here are some forms to get started. These can be printed and brought with you so that you can pre-fill out some known info ahead of time. More...


Medical Disorders
Resources
Basic InformationLookupsLatest News
E-Cigarettes Slowed Wound Healing in Animal Study3-Drug Therapy Might Be Cystic Fibrosis 'Breakthrough'Pounds Regained After Weight-Loss Op Can Tell Your Doc a LotCDC Warns of Polio-Like Virus Striking More U.S. KidsNew Nerve Stimulation Technique Might Relieve Back PainGluten-Free Craze a 'Double-Edged Sword' for Celiac PatientsHealth Tip: Know the Risks of Chicken PoxKids' Concussion Symptoms May Persist for a YearNew DNA-Based Test Approved to Help Verify Blood CompatibilityAHA: A Child's Eyes May Be a Window Into Later Heart Disease RiskGenes, Not Diet, May Be Key to Gout Flare-UpsDiabetes Drug Might Help Shield the Heart From Smog's Ill EffectsHealth Tip: Understanding MigrainesHospital Privacy Curtains May Be Home to Dangerous GermsWeight-Loss Surgery May Raise Gallstone Risk: StudyStudy Sees No Link Between Gout Drug, Kidney DiseaseHealth Tip: Prevent Mold Growth at HomeOne-Third of 'Gluten-Free' Restaurant Foods in U.S. Are Not: StudyHalf of Antibiotics Given Without Infection DiagnosisMediterranean Diet May Help Preserve Your Vision: StudyAHA: Researchers Suggest New Way to Possibly Eliminate Clogged ArteriesCan a 'Noah's Ark' of Microbes Save the World's Health?Brain Scans Suggest Pain of Fibromyalgia Isn't ImaginaryHealth Tip: Treat Your Child's AllergiesAHA: Doctors Could Do More to Help Smokers With Poor CirculationAcne's Stigma Can Take a Big Mental TollDoes Less-Invasive Surgery Make Sense for You?Type 2 Diabetes Tied to Raised Risk of Tumors, Cancer Deaths'Southern' Diet Blamed for Black Americans' Health WoesOne Football Rule Change Might Lower Concussion RiskDeep Space Travel May Damage GI Tract, Animal Study ShowsNew Drug Approved for Antibiotic-Resistant Lung DiseaseDrinking Enough Water Could Be Key to Avoiding UTIsThree New Genes Linked to Chronic Back Pain'Yo-Yo' Cardio Readings May Signal Heart RisksHealth Tip: Understanding Hip Replacement SurgeryCommon Heartburn Drugs Linked to Broken Hips in Dialysis PatientsWith 80,000 Flu Deaths Last Season, Experts Urge VaccinationHealth Tip: Manage Symptoms of AnemiaHealth Tip: Considering LASIK Surgery?Don't Turn a Blind Eye to Vision ProblemsExperimental Vaccine Shows Promise in Preventing TBAntibiotics May Cure Appendicitis -- No Operation NeededGun Victims More Likely to Die Than Other Trauma PatientsSpinal Implant Could Be Breakthrough for Paralyzed PatientsHealth Tip: Maintain Healthy Cholesterol5 Tips to Manage Your Child's AsthmaNew Compounds Might Help Stop Spread of MalariaAHA: Stiffening of Blood Vessels May Point to Dementia RiskContact Lenses May Harbor Serious, Blinding Infection
Questions and AnswersLinksBook Reviews
Related Topics

Cancer
Men's Health
Women's Health

Can 'Mono' Virus Up Odds for 7 Other Diseases?

HealthDay News
by By Alan Mozes
HealthDay Reporter
Updated: Apr 16th 2018

new article illustration

MONDAY, April 16, 2018 (HealthDay News) -- Millions of young Americans have lived through the fatigue and discomfort of mononucleosis.

Now, new research suggests, but doesn't prove, that the virus that causes the illness may be linked to an increased risk for seven other serious immune-system diseases.

Those diseases include lupus; multiple sclerosis; rheumatoid arthritis; juvenile idiopathic arthritis; inflammatory bowel disease; celiac disease; and type 1 diabetes.

"Mono" is a contagious illness that occurs most often in teens and young adults. It's caused by the Epstein-Barr virus, one of the most common human viruses.

"Epstein-Barr virus infects over 90 percent of adults, and the infection lasts for a lifetime," said study lead author Dr. John Harley.

"The new results are building a strong case that this virus is also involved in causing a number of autoimmune diseases for at least some patients," added Harley. He is director of the Cincinnati Children's Hospital Center for Autoimmune Genomics and Etiology.

"It is the kind of circumstantial evidence that is comparable to a smoking gun," he added.

And those seven diseases affect roughly 8 million Americans, Harley and his colleagues said.

However, one expert said people who have had mono shouldn't panic.

The findings "should not be a cause for alarm," said Dr. David Pisetsky, a professor of medicine at the Duke University School of Medicine in Durham, N.C.

"In modern life everyone has been exposed and infected with Epstein-Barr," he noted. "And if 99 percent of people have been exposed to Epstein-Barr, and only 0.1 percent have lupus, it means there really must be other factors at play that affect risk," Pisetsky explained.

"I really don't think it's a reason for undue concern," he added. Pisetsky is also on the scientific advisory board for the Lupus Research Alliance.

Harley's in-depth genetic analysis revealed that at the cellular level, the Epstein-Barr virus shares a number of abnormal viral on-off switches ("transcription factors") in common with those seven other illnesses.

Those transcription factors are meant to move along the human genome (DNA roadmap), jumpstarting cells into performing necessary tasks.

But the abnormal switches found in Epstein-Barr hijack this process. First, they bind to a specific protein -- known as EBNA2. Then they move about the genome in search of disease trigger points. Once docked at a respective trigger point, the risk for that particular disease goes up, the new research suggests.

Harley said he and other scientists will continue to examine additional factors that likely also contribute to autoimmune risk. Autoimmune diseases occur when your immune system mistakenly attacks your body.

As the cause of mononucleosis, Epstein-Barr is typically transmitted via saliva, giving rise to its nickname as the "kissing disease."

Kids and teens with mono may have a fever, muscle aches and sore throat. They often feel exhausted. However, many people -- especially young children -- experience no symptoms. And in most cases, mono resolves within a couple of weeks.

"The new findings stem from an extensive genetic review of potential links between known transcription factors and roughly 200 illnesses," Harley said, noting that there is preliminary indications that 10 other diseases may also be linked to the virus. "However, the study could not prove a cause-and-effect relationship."

Tim Coetzee is chief advocate for services and research with the National Multiple Sclerosis Society. He characterizes the new findings as "an important contribution."

"We need these kinds of studies to help us unravel how this virus could trigger disease," he said. "The paper is also a powerful demonstration about how detailed genetic studies can help us understand human diseases."

Careful research like this, Coetzee added, "will give us the knowledge we need to better understand the complexity of autoimmune diseases, and importantly point the way to potential prevention of these."

The study results were released online April 16 in Nature Genetics.

More information

There's more on Epstein-Barr virus at the U.S. Centers for Disease Control and Prevention.