611 W. Union Street
Benson, AZ 85602
(520) 586-0800

Health Choice Integrated Care crisis Line

AzCH Nurse Assist Line


611 W. Union Street
Benson, AZ 85602
(520) 586-0800

AzCH Nurse Assist Line


powered by centersite dot net

Getting Started
Here are some forms to get started. These can be printed and brought with you so that you can pre-fill out some known info ahead of time. More...

Health Sciences
Basic InformationLatest News
'Miracle' Young Blood Infusion Treatments Unproven, Potentially Harmful: FDAPossible Parkinson's 'Pandemic' Looms: ReportScience Puzzling Out Differences in Gut Bacteria Around the World'Mind-Reading' AI Turns Thoughts Into Spoken WordsEat What You Want and Still Stay Slim? Thank Your GenesGood News, Bad News on Levodopa for Parkinson's DiseaseNature or Nurture? Twins Study Helps Sort Out Genes' Role in DiseaseBeing Bullied May Alter the Teen BrainFDA Warns Companies on Dangerous, Unapproved Stem Cell TreatmentsGene Tweaking Prevented Obesity in MiceApproach That New Gene Testing Kit With CautionResearch on Almost 2,000 Brains Brings Insight Into Mental IllnessRestoring Hair Growth on Scarred Skin? Mouse Study Could Show the WayParkinson's Gene Therapy Wires New Brain CircuitsNext for Disabling Back Pain? New Discs From Patients' Own CellsSkin 'Glow' Test Might Someday Spot Disease Risk EarlyComputer-Brain Link Helps 'Locked In' People Chat, Surf WebCould a Natural Protein Help Fight Obesity?Blood Test May One Day Help Track Concussion RecoveryThe Bigger the Brain, the Bigger the Tumor Risk?Gene Therapy for Parkinson's Symptoms Shows PromiseCould Same-Sex Couples Have Babies With Shared DNA? Study Hints It's PossibleMany Americans Curious, But Wary, About Gene TestingAHA: New Report Explores Genes Behind Congenital Heart DiseaseScientists Find 500 More Genes That Influence Blood PressureALS Affects the Mind, Not Just the BodyScientists Finally Get Around to Finding Procrastination's Home in the BrainGene 'Editing' in Dog Study Shows Promise for Kids With Muscular DystrophyGut Enzyme Could Help Solve U.S. Blood Shortages'Fat' Mouse Test Failure Yields New Obesity ClueIs Evolution of the Human Brain to Blame for Some Mental Disorders?Scientists Trace Link Between Head Injuries and Parkinson'sAHA: Scientists May Have Cleared Gene Therapy HurdleAlmost 1,300 Genes Seem Tied to Academic SuccessBrains May Be as Unique as Fingerprints'Heading' Soccer Balls May Be Bad for BalanceScientists Target Cellular 'Fountain of Youth' to Extend Mouse Life SpanThose At-Home DNA Tests Are an Imperfect ScienceScientists Spot Gene Linking Down Syndrome, Early Alzheimer'sMassive Study Finds Same Genes Drive Many Psychiatric ConditionsThyroid Cancer Survivors at Risk for Heart DiseaseBetter Diet, Bigger Brain?Primary Care Providers Have Mixed Views on Genetic TestsFDA Targets Clinics Offering Unapproved Stem Cell TherapiesRestless Legs Linked to Brain ChangesContact Sports May Alter the Brain, Scans SuggestJust One Concussion Could Raise Parkinson's RiskLove Your Hair Color? You Have Over 100 Genes to Thank.Too Much Sitting Could Raise Brain RisksBusting Myths Surrounding Cancer and Genetic Testing
Questions and AnswersLinksBook Reviews
Related Topics

Medical Disorders
Mental Disorders
Mental Health Professions

Major Project Completes Genetic 'Map' of 33 Cancers

HealthDay News
by -- Robert Preidt
Updated: Apr 5th 2018

new article illustration

THURSDAY, April 5, 2018 (HealthDay News) -- In what could prove to be a big advance in cancer care, a consortium of scientists said it has mapped the genetic blueprints of 33 cancer types.

The hope: that DNA similarities observed between 10,000 tumor samples -- arising in different sites in the body -- might allow targeted treatments to fight cancers no matter where they occur.

Ideally, "patients will have the best shot at successful treatment if their tumors can first be classified according to their genomic and molecular makeup," explained scientist Dr. Christopher Benz.

He's a member of The Cancer Genome Atlas (TCGA) Network, the group that produced the new report. He's also a professor of cancer and developmental therapeutics at the Buck Institute for Research on Aging in San Francisco.

Speaking in an institute news release, Benz said the TCGA insights "will provide a new foundation for future cancer research efforts and clinical trials."

That's because for years, scientists and oncologists have been moving away from the notion of categorizing and treating cancers based on where in the body they occur.

Instead, projects like the TCGA have raised awareness that tumors can share the same basic genetic makeup -- even if they occur in discrete locales. Targeting treatments to these shared genetics might therefore be far more effective an approach than the traditional "site-specific" method.

The new work, collectively called the PanCancer Atlas, was published April 5 in a series of papers in Cell journals.

The $300 million effort was funded by the U.S. National Institutes of Health and involved about 150 scientists at more than two dozen centers across North America.

"This project is the culmination of more than a decade of groundbreaking work," NIH Director Dr. Francis Collins said in an NIH news release. "This analysis provides cancer researchers with unprecedented understanding of how, where and why tumors arise in humans, enabling better informed clinical trials and future treatments."

Carolyn Hutter directs the Division of Genome Sciences at the National Human Genome Research Institute. Speaking in the NIH news release, she said, "TCGA was the first project of its scale to characterize -- at the molecular level -- cancer across a breadth of cancer types."

For example, the scientific effort has already uncovered strong molecular similarities between "squamous cell" cancers of the head and neck, lung, bladder, cervix and esophagus. That means these cancers might someday be classed together, even though they arise in different parts of the body.

But in another finding, it was discovered that cancers in the kidneys actually varied widely in their molecular composition -- so treating kidney cancer may not be a "one size fits all" proposition.

All of these insights should help doctors focus treatments to hit genetic or molecular vulnerabilities unique to particular cancers.

"This new molecular-based classification system should greatly help in the clinic," agreed TCGA participant Charles Perou. He's a professor of molecular oncology at the University of North Carolina's Lineberger Comprehensive Cancer Center.

"These findings also provide many new therapeutic opportunities, which can and will be tested in the next phase of human clinical trials," Perou said in a UNC news release.

The next step could be to sort out why particular tumor types develop, and how they then progress.

Having the PanCancer Atlas on hand "is really important for us to look in future studies at why these alterations are there, and to predict outcomes for patients," another UNC participant, geneticist Katherine Hoadley, explained in the university news release.

More information

The U.S. National Cancer Institute has more on cancer.