611 W. Union Street
Benson, AZ 85602
(520) 586-0800

Health Choice Integrated Care crisis Line
1-877-756-4090

NurseWise 24-Hour Crisis Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530



SEABHS
611 W. Union Street
Benson, AZ 85602
(520) 586-0800

NurseWise 24-Hr Crisis Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530


powered by centersite dot net

Getting Started
Here are some forms to get started. These can be printed and brought with you so that you can pre-fill out some known info ahead of time. More...


Health Sciences
Resources
Basic InformationLatest News
Why Your Nose May Be Key to Parkinson's RiskEvolution Not Over for HumansBrain Scans Offer Clues to Why Some Teens Pile on PoundsNew Clues to Why Yawns Are ContagiousNew Hope From Old Drugs in Fight Against Parkinson'sFirst Gene Therapy Approved in U.S.Awake for Aneurysm Brain Surgery, Better Results?Does Autism Risk Reside in Cells' Energy Engines?More Evidence Contact Sports Can Affect the BrainVirtual House Calls for Speedy, Effective Parkinson's CareSeven Imaging Biomarkers Tied to Cognition in Male FightersDiabetes Drug Shows Promise Against Parkinson'sCombined MRI Might Help Predict Brain Damage in BoxersMedical Reality Catches Up to Science FictionNoninvasive Brain Test May Pinpoint Type of DementiaIn Mice, Brain Cells Discovered That Might Control AgingScans May Show Consciousness in 'Comatose' PatientsBoxers, MMA Fighters May Face Long-Term Harm to Brain: StudyFDA Panel OKs What May Soon Be First Gene Therapy Approved in U.S.Early Parkinson's May Prompt Vision ProblemsWhole-Genome Sequencing of Uncertain Clinical UtilityCould Shift Work Damage Your DNA?Gene Sequencing May Reveal Risks for Rare DiseasesRogue Genes May Cause Some ALS CasesSticky Brain 'Plaques' Implicated in Alzheimer's AgainEven Your Bones Can Get Fat, Mouse Study SuggestsDoes a Low-Fat Dairy Habit Boost Parkinson's Risk?MicroRNA Biomarker Signature Identified for Allergic AsthmaHaywire Immune Cells May Help Cause BaldnessRegion in Brain Associated With Fear of Uncertain FutureBrain Scans Spot Where Fear and Anxiety LiveGene Therapy Might Someday Mend Badly Broken BonesLife Expectancy Slighter Shorter With Parkinson's, DementiaStudy Looks at Parkinson's Effect on Life SpanBody Cooling May Help Brain After Cardiac ArrestDo You Overeat? Your Brain Wiring May Be WhyGene Mutation May Speed Alzheimer's DeclineIs This Enzyme Making You Fat?Type 2 Diabetes May Be Bad for Brain Health'Brain Age' May Help Predict When You'll DieParkinson's Disease May Originate in Gut, Study SaysBlood-Based Genome Testing Feasible for Rapid Mutation AssayBlood Test May Gauge Death Risk After Surgery150-Year-Old Drug May Shorten 'Off' Time for Parkinson's PatientsBrain May Be Organized by Functions, Not Body PartsBody Temperature Might Give Clues to ComaCould Young Blood Boost the Aging Brain?A 'Brainwave' to Help Fight PTSDDizziness in Parkinson's May Be Due to Cerebral HypoperfusionMisunderstood Gene Tests May Lead to Unnecessary Mastectomies
Questions and AnswersLinksBook Reviews
Related Topics

Medical Disorders
Mental Disorders
Mental Health Professions

Does Autism Risk Reside in Cells' Energy Engines?

HealthDay News
by -- Mary Elizabeth Dallas
Updated: Aug 23rd 2017

new article illustration

WEDNESDAY, Aug. 23, 2017 (HealthDay News) -- Mitochondria, the power plants of human cells, may play a significant role in autism risk, new research suggests.

Not only that, ancient human migration patterns may have predisposed some groups to a greater risk for the developmental disorder, the scientists added.

"Our findings show that differences in mitochondrial function are important in ASD [autism spectrum disorder]," said study leader Douglas Wallace. He directs the Center for Mitochondrial and Epigenomic Medicine at Children's Hospital of Philadelphia.

"Our team demonstrates that a person's vulnerability to ASD varies according to their ancient mitochondrial lineage," he added.

For the study, researchers examined the genetic data of 1,624 autism patients and 2,417 healthy parents and siblings.

Within a human cell, mitochondria are the structures that supply energy to the entire cell. They have their own DNA, called mtDNA. That DNA is separate from the DNA found inside the nucleus of cells, which is known as nDNA.

Mitochondrial DNA is inherited only through one parent -- the mother. By examining mtDNA variations among populations around the world, scientists have been able to reconstruct human migrations and evolution patterns over thousands of years. They've sorted these mtDNA variations in genetic subgroups, the study authors said.

The researchers found that six European subgroups had significantly higher risks of autism than the most common European group. The researchers also found that two Asian and Native American subgroups were at increased risk for autism.

Migration, changes in nutrition and other environmental influences can increase the risk for disease even further, the researchers explained.

The researchers said their findings, which suggest that mtDNA energy could play a major role in autism risk, might lead to new treatments for this group of neurological disorders.

"There is increasing interest in developing metabolic treatments for known mtDNA diseases," Wallace said. "If ASD has a similar etiology [set of causes], then these same therapeutic approaches may prove beneficial for ASD."

The findings were study published online Aug. 23 in the journal JAMA Psychiatry.

More information

Autism Speaks provides more information on risk factors for autism.