611 W. Union Street
Benson, AZ 85602
(520) 586-0800

Health Choice Integrated Care crisis Line
1-877-756-4090

NurseWise 24-Hour Crisis Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530



SEABHS
611 W. Union Street
Benson, AZ 85602
(520) 586-0800

NurseWise 24-Hr Crisis Line
1-866-495-6735

NAZCARE Warm Line
1-888-404-5530


powered by centersite dot net

Getting Started
Here are some forms to get started. These can be printed and brought with you so that you can pre-fill out some known info ahead of time. More...


Medical Disorders
Resources
Basic InformationLookupsLatest News
Streptococcal Throat Infection Linked to Mental DisordersCognitive Decline Linked to Visual Field VariabilityRiboflavin Shows Positive Effect for Migraine in AdultsPromising Results for Drug to Fight Arthritis Linked to PsoriasisKidneys From Deceased Diabetics Might Ease Organ Shortage: StudyNew Cholesterol Fighting Meds Target Key GeneEye Problems May Be Tied to Zika, Lab Study SuggestsATS: Bronchial Thermoplasty Has Lasting Benefits for AsthmaSleepless Nights Could Pose Heart Risk DangersHospital Protocol Helps Thwart Serious InfectionZika Arrived in Florida at Least Four Different WaysKnow the Signs of Thyroid TroubleStudies Spotlight Diet, Supplements for Knee PainFunctional Interaction Seen for Dietary Carbohydrates With AMDTaking Opioids Before Knee Surgery Could Raise Pain LaterATS: First Abx Rx Doesn't Work for ~25% of Pneumonia CasesActemra Approved for Certain Blood Vessel InflammationStudy Casts Doubt on Need for Statins in the 'Healthy Old'First-Try Antibiotics Now Fail in 1 in 4 Adult Pneumonia CasesOvercrowded ERs Risky for Some Seriously Ill PatientsHigh Vitamin K1 Intake Linked to Reduced Cataract RiskPoverty Could Make Lupus Even WorseCDC: Crypto Outbreaks Linked to Pools Have Doubled Since 2014Could Cancer Drug Gleevec Help With Severe Asthma?Zika Mosquito Can Transmit Other Viruses, TooFDA OKs Kalydeco for Additional Mutations in Cystic FibrosisKalydeco Approval Widened for More Types of Cystic FibrosisAnother Step Toward Ebola ProtectionThe Water's Not Fine: U.S. Pool-Linked Infection Doubles in 2 YearsJust 2 Weeks on the Couch Can Trigger Body's DeclineGene Therapy Might Someday Mend Badly Broken Bones'Healthy Obese' May Be a MythNo Evidence Steroids Benefit Symptomatic Knee OsteoarthritisHeart Attack Risk Spikes After Respiratory Infection, Study FindsFor Inflamed Pancreas, Eating Right Away May Be Best MedicineFindings Support More Targeted Approach to Cholesterol ScreensHouston, You Have a 'Superbug'Forget Steroid Shots for Long-Term Relief of Arthritic KneesFDA Approves New Device to Treat Esophageal AtresiaMany U.S. Travelers Skip Measles Shots, Despite Infection RiskMany Under 40 May Not Need Regular Cholesterol Checks: StudyNew Device Approved for Esophageal Birth DefectACP: Recommendations Updated for Low Bone Density TreatmentMosquito-Borne Illnesses May Not Be Limited to TropicsArthroscopy for Degenerative Knees Deemed Seldom EffectiveBioengineered Intraabdominal Endocrine Pancreas FeasibleAllergies Getting Worse? Blame Climate ChangeA 2nd Life for Risky Kidney Transplants?Blood Vessel-Clearing Procedure Riskier on Weekends: StudyMultidrug-Resistant TB Set to Increase Through 2040
Questions and AnswersLinksBook Reviews
Related Topics

Cancer
Men's Health
Women's Health

Testosterone May Protect Men From Allergic Asthma

HealthDay News
by -- Mary Elizabeth Dallas
Updated: May 9th 2017

new article illustration

TUESDAY, May 9, 2017 (HealthDay News) -- Testosterone -- the male sex hormone -- may be the reason why so many more women have asthma than men, new research suggests.

The study found that testosterone suppresses an immune system cell involved in allergic asthma.

Allergic asthma is an inflammatory condition that causes the airways to swell, making it hard to breathe. The swelling and inflammation is triggered by an allergic reaction.

Before puberty, the condition is more common among boys than girls. Afterwards, however, it is twice as prevalent and more severe among women than men, the researchers explained.

"There is a very interesting clinical observation that women are more affected and develop more severe asthma than men, and so we tried to understand why this was happening," said study leader Cyril Seillet, from the Walter and Eliza Hall Institute in Melbourne, Australia.

The international team of scientists found that testosterone blocks the production of a type of immune cell that triggers allergic asthma, called innate lymphoid cells -- or ILC2s.

ILC2s are found in the lungs, skin and other organs. These cells produce proteins that can lead to lung inflammation and damage when exposed to asthma allergens, such as pollen, dust mites, cigarette smoke and pet hair.

When ILC2s detect testosterone, the cells stop reproducing, the study findings showed.

"We identified that testosterone is a potent inhibitor of [ILC2s], a newly described immune cell that has been associated with the initiation of asthma," Seillet said in an institute news release.

"So in males, you have less ILC2s in the lungs and this directly correlates with the reduced severity of asthma," he explained.

"Our research shows that high levels of testosterone in males protect them against the development of allergic asthma," Seillet added.

The researchers said their finding could lead to new treatments for the inflammatory airway condition.

According to study co-author Gabrielle Belz, "Current treatments for severe asthma, such as steroids, are very broad-based and can have significant side effects." Belz is from the molecular immunology division at the Walter and Eliza Hall Institute.

"This discovery provides us with a potential new way of treating asthma, by targeting the cells that are directly contributing to the development of allergic asthma," she said in the news release.

More research needs to be done, Belz noted. But she pointed out that similar hormone-suppression tactics have been used successfully for treating other diseases, such as breast cancer.

The study was published May 8 in the Journal of Experimental Medicine.

More information

The U.S. Centers for Disease Control and Prevention has more about asthma in women.